• BOTANICAL OILS
    • Cold-pressed oils
    • Infused & macerated oils
    • Essential oils
  • HERBAL WATERS
    • Floral, herbal and fruit waters
  • NUTRI POWDERS
    • Nutrient rich herbal powders
  • SERVICES
    • OEM
  • CONTACT US
  • български
    • english english
    • русский русский
    • 中文 中文
    • 日本語 日本語

  • NUTRI POWDERS
  • Nutrient rich herbal powders
  • Grapeseed Powder (vitis vinifera)
Grapeseed Powder <em>(vitis vinifera)</em>
×

Grapeseed Powder (vitis vinifera)

optimal blood flow

: customised package availabe

DOWNLOAD PRODUCT INFO SHEET

  • Finely ground mechanical extract from the seeds of Vitis vinifera (grape) post cold-press oil extraction

    Grapeseed powder is a valuable source of plant-based polyphenols, dietary fiber (>40%), proteins, vitamins, minerals and bioactive compounds (notably OPCs, catechins, epicatechins, epicatechin-3-O-gallate and phenolic acids ).

  • Regaining popularity as a medicinal plant suitable for its wide range of health benefits including protection against oxidative stress, inflammation, metabolic syndrome, cardiovascular disease, and even certain cancers. Used as an ingredient in pharmaceuticals, foods, feeds, dietary supplements and cosmetic formulations.

  • It is particularly notable for its high concentration of OPCs – extremely powerful antioxidant polyphenols.




Therapeutic Properties

  • OPCs: -proanthocyanidins with predominantly pharmacological effects including anti-oxidant, anti-microbial, anti-obesity, anti-diabetic, anti-neurodegenerative, anti-osteoarthritis, anti-cancer, and cardio- and eye-protective properties.
  • Antioxidant efficacy and bio-active composition: - grapeseed is distinguished by its rich bioactive composition, which includes not only OPCs but also other potent polyphenols such as catechins, gallic acid, and quercetin. Furthermore, it contains dietary fiber, proteins, and essential minerals. This complex profile contributes to its consistently high antioxidant capacity, which is demonstrated through prominent free radical scavenging and metal-reducing activities.
  • Disease prevention, metabolic support and anti-inflammatory properties: - a substantial body of scientific literature documents a range of beneficial effects, including anti-inflammatory, anti-obesity, anti-diabetic, hypocholesterolemic, and cardioprotective properties. These observed benefits are primarily attributed to the modulation of inflammatory cytokines and the improvement of both glucose and lipid metabolism. Furthermore, emerging evidence suggests potential for anti-cancer, neuroprotective, and gut microbiota-modulating effects.

  • Pharmaceuticals
  • Food additive
  • Dietary supplements
  • Functional ingredients
  • Animal feed



Content (INCI): 100% fine powder from cold-pressed Grape seeds (Vitis vinifera powder). No additives

A Short History of Grapes: From Sacred Vine to Seed of Strength

Few fruits carry as rich a legacy as the humble grape. Cultivated for over 8,000 years, the grapevine has been a symbol of fertility, vitality, and celebration across cultures. From the ancient vineyards of Mesopotamia and Egypt to the sun-soaked slopes of Greece and Rome, grapes were more than food—they were sacred.

In classical antiquity, the grapevine was tied to gods: Dionysus in Greece and Bacchus in Rome, both deities of wine, joy, and transformation. Wine-making was not only a craft but a cultural pillar. Yet behind the wine was a deeper treasure: the grape seed—small, hard, and powerful.

Ancient healers believed that grape seeds could promote digestion and support circulation. Ground into paste or infused in oils, they were used in remedies for skin, inflammation, and wound healing. While the flesh of the grape fermented into wine, the seeds retained a legacy of healing and renewal.

In more recent centuries, especially in the herbal traditions of **Europe and the Middle East**, grape seed infusions were used to soothe sore throats, improve skin elasticity, and support liver function. But it wasn't until the 20th century that scientists uncovered the real magic inside: proanthocyanidins—potent antioxidants that help protect cells and blood vessels.

Today, grape seed extract and powder are prized for their role in cardiovascular health, cellular protection, and anti-aging support. The once-discarded by-product of wine and oil production is now recognized as a functional super-ingredient in food, supplements, and skincare.

From sacred vine to modern nutraceutical, the grape continues to nourish, heal, and connect us to a history as deep as its roots.



* Scientific References: Grapeseed

  1. Rastegar-Moghaddam, Seyed Hamidreza et al. "Grape seed extract effects on hippocampal neurogenesis, synaptogenesis and dark neurons production in old mice. Can this extract improve learning and memory in aged animals?.": Nutritional neuroscience, 25 (2022): 1962-1972.
  2. D. Gîtea et al. "Antioxidant capacity and phenolic profile of defatted seed powder derived from organically grown vine crops.": Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Food Science and Technology (2024).
  3. G. Jayaprakasha et al. "Antibacterial and antioxidant activities of grape (Vitis vinifera) seed extracts.": Food Research International, 36 (2003): 117-122.
  4. Z. Ma et al. "Phytochemical Constituents, Health Benefits, and Industrial Applications of Grape Seeds: A Mini-Review.": Antioxidants, 6 (2017).
  5. N. Unusan et al. "Proanthocyanidins in grape seeds: An updated review of their health benefits and potential uses in the food industry.": Journal of Functional Foods, 67 (2020): 103861.
  6. Dimitris Michailidis et al. "Exploitation of Vitis vinifera, Foeniculum vulgare, Cannabis sativa and Punica granatum By-Product Seeds as Dermo-Cosmetic Agents.": Molecules, 26 (2021).
  7. Zareen S Khan et al. "Profile of Triacylglycerols, Phenols, and Vitamin E of Manjari Medika Grape Seed Oil and Cake: Introducing a Novel Indian Variety.": European Journal of Lipid Science and Technology, 122 (2020): 1900356.
  8. Y. Salem et al. "Oxidation-Driven Assembly of Phenolic Compounds from Grape Seeds Waste into Nanoparticles as Potential Anti-Inflammatory and Wound Healing Therapies..": ACS applied bio materials (2025).
  9. Dan-Dan Zhou et al. "Bioactive Compounds, Health Benefits and Food Applications of Grape.": Foods, 11 (2022).
  10. V. Di Stefano et al. "Polyphenol Characterization and Antioxidant Activity of Grape Seeds and Skins from Sicily: A Preliminary Study.": Sustainability (2022).
  11. Yan Chen et al. "Effective utilization of food wastes: Bioactivity of grape seed extraction and its application in food industry.": Journal of Functional Foods, 73 (2020): 104113.
  12. Grases et al. "Effect of consuming a grape seed supplement with abundant phenolic compounds on the oxidative status of healthy human volunteers.": Nutrition Journal, 14 (2015): 94.
  13. Balu, Muthaiya et al. "Age-related oxidative protein damages in central nervous system of rats: modulatory role of grape seed extract.": International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 23 (2005): 501-7.
  14. Wang, Jun et al. "Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease.": The Journal of neuroscience : the official journal of the Society for Neuroscience, 28 (2008): 6388-92.
  15. Zhang, Haili et al. "The impact of grape seed extract treatment on blood pressure changes: A meta-analysis of 16 randomized controlled trials.": Medicine, 95 (2016): e4247.
  16. C. Rodríguez-Pérez et al. "Grape Seeds Proanthocyanidins: An Overview of In Vivo Bioactivity in Animal Models.": Nutrients, 11 (2019).
  17. I. Țăranu et al. "Assessment of the effect of grape seed cake inclusion in the diet of healthy fattening‐finishing pigs.": Journal of Animal Physiology and Animal Nutrition, 102 (2018): e30–e42.
  18. Sevinc Akca et al. "The Effects of Grape, pomegranate, Sesame Seed Powder and Their Oils on Probiotic Ice Cream: Total phenolic contents, antioxidant activity and probiotic viability.": Food Bioscience (2021).
  19. Madhavi Gupta et al. "Grape seed extract: having a potential health benefits.": Journal of Food Science and Technology, 57 (2019): 1205-1215.
  20. Miao Liu et al. "Effects of Grape Seed Proanthocyanidin Extract on Obesity.": Obesity Facts, 13 (2020): 279 - 291.
  21. Antje R. Weseler et al. "Masquelier’s grape seed extract: from basic flavonoid research to a well-characterized food supplement with health benefits.": Nutrition Journal, 16 (2017).
  22. L. Sochorová et al. "Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers.": Molecules, 25 (2020).
  23. G. N. Costa et al. "Grape seed pomace as a valuable source of antioxidant fibers..": Journal of the science of food and agriculture, 99 (2019): 4593-4601 .
  24. I. Țăranu et al. "Active ingredients from oil by-products modulate spleen inflammatory and antioxidant response in pigs.": Archiva Zootechnica, 23 (2020): 81 - 97.
  25. É. Szabó et al. "Correlations between Total Antioxidant Capacity, Polyphenol and Fatty Acid Content of Native Grape Seed and Pomace of Four Different Grape Varieties in Hungary.": Antioxidants, 10 (2021).
  26. Skovgaard, G R Lange et al. "Effect of a novel dietary supplement on skin aging in post-menopausal women.": European journal of clinical nutrition, 60 (2006): 1201-6.
  27. Schön, Christiane et al. "Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers.": Nutrients, 13 (2021).
  28. Ward, Natalie C et al. "The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trial.": Journal of hypertension, 23 (2005): 427-34.
  29. M. Akaberi et al. "Grapes (Vitis vinifera) as a Potential Candidate for the Therapy of the Metabolic Syndrome.": Phytotherapy Research, 30 (2016): 540 - 556.
  30. Hua Li et al. "Comparative study of antioxidant activity of grape (Vitis vinifera) seed powder assessed by different methods.": Journal of Food and Drug Analysis (2020).
  31. K. Seo et al. "Chardonnay grape seed flour supplemented diets alter intestinal microbiota in diet‐induced obese mice.": Journal of Food Biochemistry, 41 (2017).
  32. Y. Salem et al. "Multi-Step Biomass Fractionation of Grape Seeds from Pomace, a Zero-Waste Approach.": Plants, 11 (2022).
  33. Ramin Mahdipour et al. "The benefits of grape seed extract in neurological disorders and brain aging.": Nutritional Neuroscience, 26 (2022): 369 - 383.
  34. M. L. Cádiz-Gurrea et al. "Cocoa and Grape Seed Byproducts as a Source of Antioxidant and Anti-Inflammatory Proanthocyanidins.": International Journal of Molecular Sciences, 18 (2017).
  35. L. Sochorová et al. "The Study of Antioxidant Components in Grape Seeds.": Molecules, 25 (2020).
  36. Qi An et al. "Prospects for Proanthocyanidins from Grape Seed: Extraction Technologies and Diverse Bioactivity.": Food Reviews International, 39 (2021): 349 - 368.
  37. Z. Antunović et al. "The Effect of Grape Seed Cake as a Dietary Supplement Rich in Polyphenols on the Quantity and Quality of Milk, Metabolic Profile of Blood, and Antioxidative Status of Lactating Dairy Goats.": Agriculture (2024).
  38. H. Lutterodt et al. "Fatty acid composition, oxidative stability, antioxidant and antiproliferative properties of selected cold-pressed grape seed oils and flours..": Food chemistry, 128 (2011): 391-9 .
  39. H. Habib et al. "Grape seed proanthocyanidin extract inhibits DNA and protein damage and labile iron, enzyme, and cancer cell activities.": Scientific Reports, 12 (2022).
  40. Alexander Vasiliev et al. "Whole Wheat Bread with Grape Seed Powder.": Journal of Global Innovations in Agricultural Sciences (2025).
  41. Yavor Ivanov et al. "Nutritional and Functional Values of Grape Seed Flour and Extract for Production of Antioxidative Dietary Supplements and Functional Foods.": Molecules, 30 (2025).
  42. Mariana A. Andrade et al. "Pomegranate and grape by-products and their active compounds: Are they a valuable source for food applications?.": Trends in Food Science & Technology (2019).
  43. Hongqian Chu et al. "Grape-seed proanthocyanidins inhibit the lipopolysaccharide-induced inflammatory mediator expression in RAW264.7 macrophages by suppressing MAPK and NF-κb signal pathways..": Environmental toxicology and pharmacology, 41 (2016): 159-66 .
  44. Maryam Parandoosh et al. "The effects of grape seed extract (Vitis vinifera) supplement on inflammatory markers, neuropeptide Y, anthropometric measures, and appetite in obese or overweight individuals: A randomized clinical trial.": Phytotherapy Research, 34 (2019): 379 - 387.
  45. Y. Yılmaz et al. "Health aspects of functional grape seed constituents.": Trends in Food Science and Technology, 15 (2004): 422-433.
  46. Kangliang Sheng et al. "Grape seed proanthocyanidin extract ameliorates dextran sulfate sodium-induced colitis through intestinal barrier improvement, oxidative stress reduction, and inflammatory cytokines and gut microbiota modulation..": Food & function (2020).
  47. Veronica D’Eusanio et al. "Waste By-Product of Grape Seed Oil Production: Chemical Characterization for Use as a Food and Feed Supplement.": Life, 13 (2023).
  48. H. Levent et al. "Physicochemical and sensory quality of gluten‐free cakes supplemented with grape seed, pomegranate seed, poppy seed, flaxseed, and turmeric.": Journal of Food Processing and Preservation (2020).
  49. K. Charradi et al. "Safety evaluation, anti-oxidative and anti-inflammatory effects of subchronically dietary supplemented high dosing grape seed powder (GSP) to healthy rat..": Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 107 (2018): 534-546 .
  50. Javaid Ashraf Nowshehri et al. "Blessings in disguise: Bio-functional benefits of grape seed extracts.": Food Research International, 77 (2015): 333-348.
  51. T. K. Junior et al. "Optimization of the Green Chemistry-like Extraction of Phenolic Compounds from Grape (Vitis labrusca L.) and Blackberry (Rubus fruticosus L.) Seeds with Concomitant Biological and Antioxidant Activity Assessments.": Plants, 12 (2023).
  52. Kangliang Sheng et al. "Alleviation effects of grape seed proanthocyanidin extract on inflammation and oxidative stress in a D-galactose-induced aging mouse model by modulating the gut microbiota..": Food & function (2022).
  53. R. Nallathambi et al. "Proanthocyanidin-Rich Grape Seed Extract Reduces Inflammation and Oxidative Stress and Restores Tight Junction Barrier Function in Caco-2 Colon Cells.": Nutrients, 12 (2020).
  54. A. Ukom et al. "Grapefruit peel powder as a functional ingredient in cake production: Effect on the physicochemical properties, antioxidant activity and sensory acceptability of cakes during storage.": International Journal of Gastronomy and Food Science (2022).
  55. Muhittin Zengin et al. "Determination of Lipophilic Vitamins and Phytosteroles Contents of Grape Seed Powder and Meal.": (2022).
  56. N. Choi et al. "Grape seed powder increases gastrointestinal motility.": International Journal of Medical Sciences, 19 (2022): 941 - 951.
  57. Chenlu Yang et al. "Processing technologies, phytochemical constituents, and biological activities of grape seed oil (GSO): A review.": Trends in Food Science & Technology (2021).
  58. G. Pistol et al. "Bioactive compounds from dietary whole grape seed meal improved colonic inflammation via inhibition of MAPKs and NF-kB signaling in pigs with DSS induced colitis.": Journal of Functional Foods, 66 (2020): 103708.

  • HOME
  • KNOW US